10 Biggest Mid-Day Losers For Tuesday - Centene (NYSE:CNC), Karyopharm Therapeutics (NASDAQ:KPTI)

Tonix Pharmaceuticals Holding Corp. TNXP shares dropped 54.1 percent to $1.00 as the company disclosed that its Phase 3 clinical study, AFFIRM, missed the primary efficacy endpoint.
Karyopharm Therapeutics Inc KPTI shares dropped 14.1 percent to $9.12 after the company reported Phase 2b STORM results.
Performance Sports Group Ltd PSG declined 10.1 percent to $3.20 as the company reported the termination of shareholder nomination agreement with Sagard Capital Partners, L.P.
Viewray Inc VRAY shares fell 9.9 percent to $3.65. Viewray shares have climbed 84.74 percent over the past 52 weeks, while the S&P 500 index has gained 10.69 percent in the same period.
Rayonier Advanced Materials Inc RYAM shares declined 9.3 percent to $11.08.
Centene Corp CNC shares dropped 6.7 percent to $64.05. Leerink Swann downgraded Centene from Outperform to Market Perform.
Medpace Holdings Inc MEDP fell 4.9 percent to $29.20. Jefferies initiated coverage on Medpace with a Hold rating, while Baird initiated coverage on the stock with a Neutral rating.
COMSCORE, Inc. SCOR dropped 4.7 percent to $30.33. SunTrust Robinson Humphrey downgraded COMSCORE from Buy to Neutral.
PAREXEL International Corporation PRXL fell 3.3 percent to $66.43. UBS downgraded PAREXEL from Buy to Neutral.
Marvell Technology Group Ltd. MRVL shares slipped 3.3 percent to $12.58 after the company announced mixed results for the second quarter. While adjusted EPS came in above expectations, revenue fell shy of the estimates.

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