Regeneron, Sanofi Announce UnitedHealth Group to Provide Preferred Access Praluent Injection

Regeneron Pharmaceuticals, Inc.

and Sanofi today announced that UnitedHealth Group

will provide preferred access to Praluent® (alirocumab) Injection through OptumRx and UnitedHealthcare for Commercial, Medicare, and Managed Medicaid patients. Praluent is the only PCSK9 inhibitor preferred across UnitedHealth Group formularies. This decision, when combined with prior favorable coverage decisions at Express Scripts, Aetna and other insurers, provides for access to flexible dosing with Praluent on formularies covering more than 100 million patients in the United States. Praluent is the only PCSK9 inhibitor currently available in two doses, that allows a healthcare provider to adjust the dose based on their patient's LDL cholesterol lowering needs. Praluent, the first PCSK9 inhibitor available in the U.S., is indicated as an adjunct to diet and maximally tolerated statin therapy for the treatment of adults with heterozygous familial hypercholesterolemia (HeFH) or clinical atherosclerotic cardiovascular disease (ASCVD) who require additional lowering of low-density lipoprotein (LDL) cholesterol. ASCVD is defined as a build-up of plaque in the arteries which can lead to reduced blood flow and a