Onconova Presents Positive Data rom Phase 2 Combination Trial of Oral Rigosertib and Azacitidine at #ASH2015

Onconova Therapeutics, Inc.

today announced the presentation of data from an ongoing Phase 1/2 clinical trial of oral rigosertib and azacitidine in higher-risk myelodysplastic syndromes (HR-MDS) at the 57th American Society of Hematology (ASH) Annual Meeting in Orlando, Florida. "The high response rate observed in the 09-08 combination trial is impressive," said Lewis R. Silverman, M.D., investigator in the trial and Associate Professor of Medicine, Hematology and Medical Oncology, at the Icahn School of Medicine at Mount Sinai.  "Furthermore, the tolerability profile of oral rigosertib and azacitidine suggests that this combination could be used in HR-MDS.  These results provide strong support for the advancement of oral rigosertib into late-stage clinical trials."