Morning Market Losers

shares tumbled 80.75 percent to $0.643 after the company reported that its evofosfamide studies did not meet primary endpoints.

shares dipped 30.61 percent to $58.05 on mixed sickle cell data results presented at the ASH 2015.

shares fell 18.46 percent to $37.24 after the company reported positive GBT440 Phase 1/2 data.

shares dropped 14.57 percent to $52.87 after the company reported data from ongoing phase 1 trial of AG-120. The company also announced data from ongoing Phase 1/2 trial of AG-221.

shares fell 11.64 percent to $13.51.

shares declined 6.08 percent to $527.10. Chipotle reported Friday that the recent e Coli incident had an adverse impact on financial and operating results during the fourth quarter. Cowen & Company downgraded Chipotle from Outperform to Market Perform and lowered the price target from $775.00 to $515.00.

shares fell 1.68 percent to $9.09 after the company issued a weak preliminary results for the third quarter.