Moffitt Cancer Center and Ignyta, Inc. Enter into Cancer Research Collaboration for RXDX-106

Moffitt Cancer Center and Ignyta, Inc.

announced today that they have entered into a research collaboration relating to RXDX-106, Ignyta's small molecule, pseudo-irreversible inhibitor of TYRO3, AXL, Mer (TAM) and cMET that is in late stage preclinical development. The collaboration, which will be conducted in the labs of Eric B. Haura, M.D., director of the Lung Cancer Center of Excellence and leader of the Chemical Biology and Molecular Medicine Program at Moffitt, will explore and develop novel protein based diagnostic assays that can assess RXDX-106 signaling activity in relevant solid tumors and associated tumor microenvironments. "This exciting collaborative partnership with Ignyta will lead to a better understanding of the potential mechanisms of action of RXDX-106 by employing our expertise in cancer proteomic technology," said Haura. "We continue to work diligently to progress RXDX-106 and the other product candidates we acquired from Teva earlier this year," said Robert Wild, Ph.D., Ignyta's Chief Scientific Officer and Senior Vice President, Research. "Ignyta's vision is to be a guiding biotechnology company in precision medicine. We are pleased to be able to collaborate with a world class investigator such as Dr. Haura and his team on the exciting biology relating to RXDX-106."