Five Prime Therapeutics Announces Initial Data From Ongoing Phase 1b Trial of FP-1039 in Squamous NSCLC, Mesothelioma

Five Prime Therapeutics, Inc.

announced that initial data from GlaxoSmithKline's

ongoing Phase 1b clinical trial of FP-1039/GSK3052230, an FGF ligand trap, in patients with squamous non small cell lung cancer (sqNSCLC) and mesothelioma were featured today in an oral presentation by Dr. Pilar Garrido at the World Conference on Lung Cancer 2015 in Denver. The presentation titled, "FP1039/GSK3052230 with chemotherapy in patients with fibroblast growth factor (FGF) pathway deregulated squamous NSCLC or MPM," included study data through August 5, 2015. "There is a significant need for more treatment options for patients with metastatic sqNSCLC and unresectable malignant pleural mesothelioma," said Paul K. Paik, M.D, a medical oncologist and lung cancer specialist at Memorial Sloan Kettering Cancer Center and an investigator in the trial. "We are hopeful that a targeted agent like FP-1039/GSK3052230 may be able to show efficacy against these difficult to treat tumors as well as an acceptable safety profile. We look forward to the full results once the trial is completed." The Phase 1b trial being conducted by GSK is evaluating