Benzinga's Top #PreMarket Gainers

shares climbed 18.76 percent to $9.75 in pre-market trading following the announcement of positive results in second Phase 3 trial of plecanatide in patients with CIC.

shares rose 18.18 percent to $2.21 in pre-market trading following the introduction of the company's Imperium™ platform of instant patch pumps for insulin, the first instant patch pump for insulin in the world. Lincoln Park Capital will purchase $5 million of Unilife shares at $1.79 per share.

gained 13.42 percent to $8.96 in pre-market trading after the company reported stronger-than-expected earnings for the second quarter.

shares climbed 6.35 percent to $83.75 in pre-market trading after the company reported better-than-expected earnings for the fourth quarter.