Benzinga's Top #PreMarket Losers

Shire plc

shares slipped 24.47% to $184.72 in pre-market trading as AbbVie

said it will reconsider its merger agreement due to proposed changes in tax regulations. American Airlines Group

fell 4% to $30.25 in pre-market trading after rising 10.25% on Tuesday. AbbVie

shares declined 3.93% to $52.00 in pre-market trading as the company said it will reconsider its merger agreement with Shire due to proposed changes in tax regulations. Linear Technology

shares declined 3.66% to $37.60 in pre-market trading after the company reported downbeat fiscal first-quarter earnings.