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Horizon Pharma (NASDAQ: HZNP) surged 20.91% to $17.75 in the pre-market session after the company announced its plans to acquire privately held Vidara Therapeutics International for around $660 million.

Exact Sciences (NASDAQ: EXAS) surged 10.26% to $15.90 in pre-market trading following the published results of colon cancer screening test.

Compugen (NASDAQ: CGEN) shares gained 4.37% to $11.95 in the pre-market after Jefferies initiated coverage on the stock with a Buy rating and a $17.00 price target.

Juniper Networks (NYSE: JNPR) shares jumped 2.51% to $26.56 in pre-market trading after Wells Fargo upgraded the stock from Market Perform to Outperform.

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