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Hyperdynamics (NYSE: HDY) shares tumbled 75.03% to $1.31 after Tullow asserted a Force Majeure event on its offshore Guinea project.

Geron (NASDAQ: GERN) dropped 66.03% to $1.49 on the US FDA's IND clinical hold notice for Imetelstat.

China Techfaith Wireless Communication Technology (NASDAQ: CNTF) shares slipped 21.53% to $2.15 after the company reported Q4 results.

Synta Pharmaceuticals (NASDAQ: SNTA) shares tumbled 17.42% to $4.36 after gaining 4.35% on Tuesday. Stifel Nicolaus downgraded the stock from Hold to Sell.

Zogenix (NASDAQ: ZGNX) declined 15.42% to $3.84 after jumping 11.82% on Tuesday.

Express (NYSE: EXPR) dipped 12.72% to $15.92 after the company reported downbeat Q4 earnings and issued a weak forecast.

MagnaChip Semiconductor (NYSE: MX) shares tumbled 11.60% to $12.67 after the company reported non-reliance on previously-issued financial statements and withdrew its outlook for the fourth quarter.

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