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Compugen (NASDAQ: CGEN) shares fell 16.83% to $11.81 in the pre-market trading after the company announced a proposed public offering of ordinary shares.

Deckers Outdoor (NASDAQ: DECK) dipped 13.19% to $73.50 after the company expected a Q1 loss of $0.16 per share. Analysts at Jefferies downgraded the stock from Buy to Hold and lowered the price target from $100 to $75.

Medivation (NASDAQ: MDVN) shares dropped 9.28% to $76.68 in pre-market trading after the company reported Q4 results. Jefferies downgraded the stock from Buy to Hold.

Arena Pharmaceuticals (NASDAQ: ARNA) dipped 6.94% to $6.30 in the pre-market session after the company reported a Q4 loss of $0.11 per share.

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