Benzinga's Top #PreMarket Losers

Ryanair Holdings plc

dipped 12.79% to $ $43.90 in the pre-market session after the company cut its profit outlook for the year. Zogenix

shares dropped 9.59% to $2.64 in pre-market trading after the company narrowed its loss for the third quarter. Zogenix announced a proposed public offering of common stock. Oclaro

shares fell 0.99% to $2.01 in the pre-market trading. Oclaro's PEG ratio is -0.17. Gilead Sciences

dipped 0.66% to $70.50 after the company reported positive Phase 3 HCV treatment results in patients co-infected with HIV.