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Eli Lilly and Company
today announced that a total of 31 abstracts will be presented at the 49^th
European Association for the Study of Diabetes Annual Meeting in Barcelona,
September 23-27. In seven presentations, Lilly will share Phase III data for
dulaglutide, its investigational GLP-1 receptor agonist, and Phase II data for
LY2605541, its investigational novel basal insulin analog.
Seventeen abstracts will be presented by Boehringer Ingelheim on behalf of the
Alliance with Lilly.
Lilly will present an additional seven abstracts, including research from its
early-stage pipeline. Lilly's pipeline comprises nearly a dozen potential new
medicines for the treatment of diabetes and its related conditions,
encompassing both large and small molecules, and targeting a variety of
mechanisms.
Following are details on some of the presentations from Lilly's late-stage
pipeline.
Dulaglutide Data
Six dulaglutide abstracts will be presented, including efficacy, safety and
health outcomes data from the Phase III programme. One of these abstracts will
be given as an oral presentation. Details for the presentations are as
follows:
o Tuesday, 24 September 2013, 10:45-12:15 CEST, Oral Presentation
o Efficacy and safety of dulaglutide vs metformin in type 2 diabetes
(AWARD-3) (Santiago Tofe Povedano) [Presentation 4]
o Tuesday, 24 September 2013, 13:45-14:45 CEST, General Poster Session
o Dose-finding results in an adaptive trial of dulaglutide combined
with metformin in type 2 diabetes (AWARD-5) (Zachary Skrivanek)
[Poster No. 1003]
o Thursday, 26 September 2013, 13:45-14:45 CEST, General Poster Session
o Efficacy and safety of dulaglutide versus placebo and exenatide in
type 2 diabetes (AWARD-1) (Carol Wysham) [Poster No. 919]
o Safety and efficacy of dulaglutide vs sitagliptin after 104 weeks in
type 2 diabetes (AWARD-5) (Bruno Guerci) [Poster No. 920]
o Efficacy and safety of dulaglutide vs sitagliptin after 52 weeks in
type 2 diabetes (AWARD-5) (Michael Nauck) [Poster No. 921]
o Patient-reported outcomes with dulaglutide, exenatide, or placebo
(AWARD-1) (Kate Van Brunt) [Poster No. 985]
Novel Basal Insulin Analog (LY2605541) Data
One Phase II abstract will be presented for LY2605541. Details for the
presentation are as follows:
o Thursday, 26 September 2013, 12:30-13:30 CEST, General Poster Session
o LY2605541 exhibits a flatter glucodynamic profile than insulin
glargine at steady state in subjects with type 1 diabetes (Linda
Morrow) [Poster No. 1030]
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