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Orexigen Therapeutics (NASDAQ: OREX) moved up 4.56% to $7.57 in the pre-market session. Orexigen shares have jumped 64.17% over the past 52 weeks, while the S&P 500 index has gained 17.56% in the same period.

Tiffany & Co (NYSE: TIF) surged 2.24% to $83.50 in the pre-market session after the company reported a rise in its Q2 profit.

MannKind (NASDAQ: MNKD) soared 2.08% to $5.90 in the pre-market trading. MannKind's PEG ratio is 0.06.

Newmont Mining (NYSE: NEM) shares gained 1.89% to $33.92 in the pre-market session. Newmont Mining has a dividend yield of 3%.

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