Biggest Losers (CAEI, TBV, PARD, CRXX, HOOK, ADY)

China Architectural Engineering, Inc. (NASDAQ: CAEI) plunged 27% to $1.10 huge volume of 1.10 million shares after CAEI announced its third quarter financial results. So far this year CAEI is down over 54%.

Tiens Biotech Group (USA), Inc. (AMEX: TBV) plummeted 23% to $3.99 on 239K shares. The 52 week trading range for TBV is $0.91 - $5.64. TBV gained over 50% in the last six months.

Poniard Pharmaceuticals, Inc. (NASDAQ: PARD) tumbled 77% to $1.71 on 20.19 million shares after its pivotal phase 3 Spear trial Of Picoplatin did not meet primary endpoint.

CombinatoRx, Incorporated (NASDAQ: CRXX) plunged 39% to $0.970 on volume of 2.41 million shares. The 52 week trading range for CRXX is $0.25 - $2.60. In the last six months, CRXX gained over 32%.

Craft Brewers Alliance, Inc. (NASDAQ: HOOK) declined 23% to $2.87 on 54K shares. The 52 week trading range for HOOK is $0.85 -$4.20. So far this year, HOOK is up over 130%.

American Dairy, Inc. (NYSE: ADY) is trading at $25.80, decreased by $6.59 or 20.46% after American Dairy reported its third quarter financial results.